Meta-Analysis of Vitamin D on Inflammation in Hemodialysis Patients

A 2025 meta-analysis of eight randomized controlled trials involving 617 maintenance hemodialysis patients. The study, authored by Chen Li, synthesizes evidence on the effects of nutritional vitamin D supplementation on biomarkers like CRP, serum albumin, and iPTH. The supporting document was last updated on 2026-05-29.

Use Cases

• Training or validating models to predict the effect of vitamin D on CRP levels in dialysis patients based on the meta-analysis results.
• Benchmarking clinical trial simulation models against the reported outcomes for serum albumin and immunoreactive Parathyroid Hormone (iPTH).
• Conducting secondary analysis on the safety profile of vitamin D supplementation using the reported adverse event, hypercalcemia, and hyperphosphatemia data.

Strengths

• Focuses on a specific clinical question with a defined population of 617 patients across 8 trials.
• Reports specific quantitative outcomes, including mean differences and confidence intervals for key biomarkers like CRP and serum albumin.
• Includes a safety analysis comparing adverse events, hypercalcemia, and hyperphosphatemia between intervention and control groups.

Limitations

• The dataset is a 45.8 KB document; the underlying trial-level or patient-level data is not provided, limiting direct analysis.
• Column-level documentation is absent; field semantics must be inferred from the manuscript text after download.
• Row count is unknown, which may limit suitability assessment for machine learning applications.

Provenance

Source

figshare

Collection Method

Meta-analysis of randomized controlled trials published up to March 1, 2025, using RevMan 5.4 and Stata 17.

Time Range

Studies published up to March 2025 were included.

Freshness

Last updated 2026-05-29 06:11:38; freshness should be verified.