Supplementary File 3: Calcium-Dependent SctV-SctW Interaction Data

An Excel file (318.1 KB) containing data from a study on the molecular mechanism of bacterial type III secretion. The research, authored by Athina G. Portaliou, demonstrates that calcium ions regulate the secretion switch by modulating the affinity between gatekeeper protein SctW and export apparatus component SctV. The dataset was last updated on May 20, 2026.

Use Cases

• Modeling calcium-dependent protein-protein interactions based on the described SctV-SctW binding affinity.
• Analyzing the hierarchical secretion order of bacterial substrates based on the described regulatory switch.
• Investigating the role of gatekeeper proteins in pathogenicity based on the described SctW function.
• Studying the effect of environmental calcium signals on bacterial effector secretion based on the described mechanism.

Strengths

• Data is associated with a specific, peer-reviewed research study on a defined molecular mechanism.
• File is small (318.1 KB) and in a widely accessible XLSX format.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and specific column definitions are unknown, requiring manual inspection after download.
• Column-level documentation is absent; field semantics must be inferred from the accompanying publication.
• The 318.1 KB file size suggests a limited scope, likely containing summary or supplementary results rather than raw high-throughput data.

Provenance

Source

figshare, authored by Athina G. Portaliou.

Collection Method

Likely contains experimental data (e.g., binding affinities, secretion assays) from the described study.

Freshness

Last updated 2026-05-20 13:01:58; freshness should be verified.