Supplementary file 3_Shenfu injection in sepsis-induced acute gastrointestinal injury: a n

A narrative review summarizing mechanistic bases, preclinical findings, and clinical evidence for Shenfu Injection in treating sepsis-induced acute gastrointestinal injury. The author performed a structured literature search of major English- and Chinese-language databases, screening preclinical and clinical studies according to predefined criteria. Due to substantial heterogeneity in study design, a quantitative meta-analysis was not performed.

Use Cases

• Summarizing evidence on botanical drug mechanisms based on the review of TLR4/NF-κB pathway inhibition.
• Analyzing clinical study limitations based on the description of small sample sizes and single-center designs.
• Reviewing safety considerations for herbal preparations based on the discussion of aconite-related toxicity and quality control.

Strengths

• The review is structured around a specific clinical application: sepsis-induced acute gastrointestinal injury.
• It synthesizes evidence from both English- and Chinese-language databases, covering a broader literature base.
• The file is openly licensed under CC-BY-4.0, permitting reuse and redistribution.

Limitations

• The dataset is a single 73.0 KB PDF file, representing a limited scope of data.
• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Structured literature search and narrative review.

Freshness

Last updated 2026-05-01 05:27:44; freshness should be verified.