Meta-Analysis of Vitamin D on Microinflammation in Hemodialysis Patients

Eight randomized controlled trials involving 617 patients form the basis of this meta-analysis. The study, authored by Chen Li and published on figshare in 2026, investigates the effect of nutritional vitamin D supplementation on inflammatory markers and nutritional status in maintenance hemodialysis patients. Results indicate a significant reduction in C-reactive protein and an increase in serum albumin with vitamin D intervention.

Use Cases

• Training meta-analysis models based on aggregated clinical trial results for CRP and serum albumin.
• Validating hypotheses about vitamin D's anti-inflammatory effects in a specific patient population.
• Benchmarking clinical outcomes for nutritional interventions in chronic kidney disease.
• Informing systematic reviews on the safety profile of vitamin D regarding hypercalcemia and hyperphosphatemia.

Strengths

• Includes data from eight randomized controlled trials, a standard for clinical evidence.
• Reports specific quantitative outcomes, such as a mean difference of -3.15 for CRP reduction.
• Explicitly assesses safety outcomes like adverse events, hypercalcemia, and hyperphosphatemia.
• Uses a defined risk-of-bias assessment tool (Cochrane tool) for study evaluation.

Limitations

• The dataset is a 269.6 KB DOCX file, which is a small document rather than a raw data repository.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of published randomized controlled trials.

Time Range

Studies published up to March 1, 2025 were included.

Freshness

Last updated 2026-05-29 06:11:39; freshness should be verified.