Supplementary File 4: Calcium and SctV-SctW Interaction Data for Type III Secretion

Athina G. Portaliou's supplementary dataset, published on figshare in May 2026, investigates the molecular mechanism of the Type III secretion switch in Gram-negative pathogens. The 168.8 KB XLSX file contains data supporting the finding that calcium modulates the affinity of the SctW–SctV protein interaction to regulate secretion order. The dataset is shared under a CC-BY-4.0 license.

Use Cases

• Modeling calcium-dependent protein affinity changes based on the described SctV-SctW binding data.
• Analyzing the hierarchical secretion switch in Type III systems using the provided experimental results.
• Validating computational predictions of gatekeeper protein function in bacterial injectisomes.

Strengths

• Data is directly linked to a specific, peer-reviewed research finding on a molecular mechanism.
• The dataset is openly available under a permissive CC-BY-4.0 license.
• File size of 168.8 KB indicates a focused, manageable dataset for analysis.

Limitations

• Row count and specific column definitions are unknown, requiring manual inspection after download.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

Athina G. Portaliou via figshare.

Collection Method

Likely contains experimental data (e.g., binding affinities, mutation effects) generated to support the described study.

Freshness

Last updated 2026-05-20 13:01:59; freshness should be verified.