CEBPD Expression Data for Uterine Leiomyoma Fibrosis Analysis

Ran Duan published a supplementary Excel file on figshare on 2026-05-19. The 76.9 KB file contains data supporting research into CCAAT/enhancer-binding protein delta (CEBPD) as a potential biomarker and regulator of fibrosis in uterine leiomyoma. The data likely includes gene expression metrics, diagnostic performance statistics, and single-cell RNA sequencing analysis results.

Use Cases

• Validate CEBPD as a diagnostic biomarker for uterine leiomyoma based on ROC curve analysis results.
• Investigate the correlation between CEBPD expression and fibrotic mediators (COL1A1, COL1A2, COL3A1) mentioned in the description.
• Analyze the association between CEBPD and epithelial-mesenchymal transition (EMT) progression using the described pseudotime and correlation analyses.
• Map cellular distribution of CEBPD within the uterine leiomyoma microenvironment using the referenced single-cell RNA sequencing data.

Strengths

• Data is derived from two independent uterine leiomyoma cohorts (GSE64763, GSE95101).
• CEBPD demonstrated diagnostic accuracy with AUC values of 0.878 and 0.858 in the described cohorts.
• Analysis includes validation from single-cell RNA sequencing and clinical specimen staining.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small at 76.9 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Analysis of transcriptional profiles from public cohorts GSE64763 and GSE95101, supplemented by single-cell RNA sequencing and histological validation.

Freshness

Last updated 2026-05-19 05:38:36; freshness should be verified.