Stickleback Transcriptomic Responses to Immune Stimuli and Parasite Evolution

Supplementary file 4_Changes in gene regulation are associated with the evolution of resistance to a novel parasite.xlsx is a transcriptomics dataset from a study comparing lab-reared threespine stickleback populations with varying susceptibilities to the cestode Schistocephalus solidus. The data, authored by Lauren E. Fuess and last updated on 2026-03-18, contains results from experiments where fish were exposed to immune stimuli like alum and cestode protein. The 185.1 KB Excel file is shared under a CC-BY-4.0 license on figshare.

Use Cases

• Analyzing population-specific transcriptomic responses based on exposure to different immune stimuli described in the methods.
• Investigating the role of fibrosis-associated gene regulation in parasite defense as highlighted in the results.
• Comparing shared and divergent evolutionary pathways in immune system adaptation across stickleback populations.
• Studying the co-option of tissue damage response pathways for novel parasite resistance as discussed in the conclusion.

Strengths

• Data is associated with a detailed scientific study published on figshare, providing methodological context.
• File size is 185.1 KB, indicating a focused and likely manageable dataset for analysis.
• Dataset has a clear license (CC-BY-4.0) permitting reuse with attribution.

Limitations

• Row count and specific column names are unknown, which limits suitability assessment for specific analyses.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect bias inherent to the specific lab-reared stickleback populations and experimental stimuli used.

Provenance

Source

Lauren E. Fuess via figshare.

Collection Method

Transcriptomic analysis of lab-reared sticklebacks from three populations exposed to immune stimuli (alum, cestode protein, control).

Freshness

Last updated 2026-03-18 07:36:48; freshness should be verified.