Meta-Analysis of Vitamin D on Inflammation in Hemodialysis Patients

A meta-analysis document summarizing results from eight randomized controlled trials involving 617 maintenance hemodialysis patients. The text analyzes the effects of nutritional vitamin D supplementation on biomarkers like CRP, serum albumin, and iPTH. The document was authored by Chen Li and last updated on 2026-05-29.

Use Cases

• Reviewing evidence for vitamin D's effect on microinflammation based on CRP and TNF-α levels.
• Assessing the impact of vitamin D on nutritional status based on serum albumin changes.
• Evaluating the safety profile of vitamin D supplementation based on reported adverse events, hypercalcemia, and hyperphosphatemia.
• Conducting secondary analysis on bone metabolism markers based on iPTH data.

Strengths

• Includes data from eight randomized controlled trials, a recognized study design.
• Analyzes results from 617 total patients.
• Reports specific statistical outcomes, such as a mean difference of -3.15 for CRP reduction.

Limitations

• The dataset is a 37.9 KB DOCX file, which is a very small text summary rather than raw trial data.
• Row count and column-level documentation for underlying data are unknown.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Meta-analysis of published randomized controlled trials up to March 1, 2025.

Time Range

Studies published up to March 1, 2025 were included.

Freshness

Last updated 2026-05-29 06:11:40; freshness should be verified.