Meta-Analysis of Moringa Oleifera in Peptic Ulcer Disease: 11 Preclinical Studies

Systematic review and meta-analysis of 11 preclinical studies involving 268 animals, evaluating the therapeutic effect of Moringa oleifera extracts on peptic ulcer disease. It includes pooled analysis results such as standard mean difference (SMD = -1.42), confidence intervals, and subgroup analyses by dose and comparator.

Use Cases

• Analyze the relationship between Moringa oleifera dose and ulcer index reduction across 11 studies.
• Compare the standard mean difference (SMD) outcomes from high-dose comparisons with standard drugs versus basal controls.
• Examine heterogeneity (I²) and publication bias results from the meta-analysis methodology.
• Assess study quality using the reported SYRCLE scores ranging from 8 to 9.

Strengths

• Includes data from 11 eligible preclinical studies involving 268 animals.
• Reports specific meta-analysis results including a pooled SMD of -1.42 with a 95% CI and p-value.
• Contains subgroup analyses by dose and comparator, and assessments of heterogeneity (I²) and publication bias.

Limitations

• The dataset is a 17.7 KB document summarizing findings, not the raw experimental data.
• Limited to preclinical (rodent) studies; no clinical trial data is included.
• The review notes methodological heterogeneity among the included studies.

Provenance

Source

figshare, authored by Saheed Olatunbosun Akiode.

Collection Method

Systematic review and meta-analysis of studies from PubMed, CINAHL, Scopus, Web of Science, and Cochrane Library.

Time Range

Literature search from database inception to August 2025.

Freshness

Last updated on 2026-03-20, with literature search up to August 2025.