Supplementary file 7_Therapeutic effects of traditional Chinese medicine injections with h

A systematic review and network meta-analysis of 83 randomized controlled trials involving 8,678 participants, published until December 2025. The study evaluates the efficacy and safety of seven heat-clearing and detoxifying traditional Chinese medicine injections combined with conventional medicine for treating viral pneumonia. The analysis was conducted by Yuanchong Wang and registered with PROSPERO.

Use Cases

• Compare the relative efficacy of different traditional Chinese medicine injections based on outcomes like cough disappearance time and hospitalization duration.
• Identify the most effective treatment combinations for specific clinical markers such as interleukin-6 levels or total clinical efficacy rate.
• Assess the safety profile of herbal injections when used alongside conventional medicine based on reported adverse events.
• Inform clinical guideline development for viral pneumonia treatment based on network meta-analysis rankings.

Strengths

• Includes 83 randomized controlled trials, a substantial evidence base for analysis.
• Covers a total sample size of 8,678 participants across the included studies.
• Compares seven specific traditional Chinese medicine injections, providing a detailed comparative framework.
• Uses a Bayesian network meta-analysis methodology, allowing for indirect treatment comparisons.

Limitations

• The primary data file is a DOCX document (1.2 MB); underlying trial data is not provided in a structured, machine-readable format.
• Row count and column-level documentation for any underlying data are unknown, limiting suitability assessment.
• Freshness should be verified; the last update was 2026-05-14, but the literature search cutoff was December 2025.

Provenance

Source

figshare, authored by Yuanchong Wang.

Collection Method

Systematic review and Bayesian network meta-analysis of randomized controlled trials from eight databases.

Time Range

Literature published until 12 December 2025.

Freshness

Last updated 2026-05-14 08:23:38; literature search conducted until 12 December 2025.

Geography

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