Rat Model Data on Vascular Function and Aerobic Exercise in Emphysema

Supplementary material from a preclinical study investigating vascular dysfunction in a rat model of exacerbated emphysema. The dataset likely contains results from four groups of male Wistar rats subjected to treadmill training, measuring respiratory parameters, blood pressure, and vascular reactivity. The material was authored by fares gouzi and uploaded to figshare in May 2026.

Use Cases

• Analyze the relationship between emphysema and elevated blood pressure based on the described systolic/diastolic/mean arterial pressure measurements.
• Compare exercise-induced changes in endothelium-dependent vasorelaxation between healthy and diseased groups based on the described NO and COX pathway signaling.
• Study the impact of aerobic exercise on skeletal muscle capillarization in a disease model based on the described muscle capillarization assessments.
• Investigate disease-specific vascular remodeling by comparing vascular adaptations to exercise in control versus emphysema groups.

Strengths

• The dataset is associated with a detailed methodological description involving four distinct experimental groups.
• The study measures multiple physiological parameters, including V̇O₂max, heart rate, blood pressure, and ex vivo vascular reactivity.
• The material is openly licensed under CC-BY-4.0.

Limitations

• The dataset is very small (99.7 KB), suggesting limited scope or supplementary nature.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Experimental data from a controlled animal study using an elastase and LPS-induced emphysema (ELA-LPS) rat model.

Freshness

Last updated 2026-05-06 15:23:25; freshness should be verified.