Supplementary Material for: 3-Hydroxybutyrate Prevents Pulmonary Vein Arrhythmogenesis by

Supplementary material from a study investigating the ketone body 3-hydroxybutyrate's effect on arrhythmogenesis in rabbit pulmonary veins. The dataset likely contains images from confocal microscopy and Western blotting, showing results on reactive oxygen species, calcium homeostasis, and protein kinase II signaling. These files support the finding that 3-OHB reduces pulmonary vein spontaneous activity by modulating ionic currents and oxidative stress.

Use Cases

• Validating Western blot results for phosphorylated CaMKII expression levels
• Analyzing confocal microscopy images for cytosolic reactive oxygen species production
• Reviewing supplementary evidence for dose-dependent reductions in pulmonary vein contractility
• Assessing experimental methodology for patch-clamp and microelectrode techniques

Strengths

• Dataset is openly licensed under CC-BY-4.0, facilitating reuse
• Cross-platform presence on figshare indicates established sharing
• Material is directly linked to a peer-reviewed study with a clear mechanistic hypothesis

Limitations

• Column names and row counts are not provided, limiting structured understanding
• The dataset consists solely of TIF image files without accompanying quantitative data tables
• Metadata lacks author organization and detailed methodological documentation for the files

Provenance

Source

figshare admin karger

Collection Method

Experimental data gathered using conventional microelectrodes, patch-clamp technique, confocal microscopy, and Western blotting on isolated rabbit pulmonary vein tissues and cardiomyocytes.

Time Range

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Freshness

Last updated 2026-03-19

Geography

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