Supplementary Material for Anti-CADM1 Antibody Study in Atopic Dermatitis Mouse Model

Supplementary material for a study examining the anti-pruritic and therapeutic effects of the anti-CADM1 antibody 3E1 in NC/Nga mice with mite antigen-induced atopic dermatitis-like lesions. The material, provided as a 2.3 MB DOCX file, includes details on methods such as indocyanine green imaging, immunostaining, Western blotting, and behavioral analysis of scratching. It was uploaded by figshare admin karger and last updated on 2026-05-04.

Use Cases

• Analyzing the systemic distribution of a therapeutic antibody based on indocyanine green imaging and immunostaining data.
• Evaluating the effect of an antibody on scratching behavior based on video-recorded duration measurements.
• Studying the improvement of dermatitis symptoms based on macroscopic records of erythema and crust formation.

Strengths

• Material is associated with a peer-reviewed study describing a specific experimental protocol.
• Data is openly available under a CC-BY-4.0 license for reuse and redistribution.
• File size of 2.3 MB suggests the document contains detailed textual and potentially graphical supplementary information.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset consists of a single DOCX file, which may require specific software for access and parsing.

Provenance

Source

figshare

Collection Method

Experimental study using NC/Nga mice, mite antigen application, antibody administration, and behavioral recording.

Freshness

Last updated 2026-05-04 09:55:15; freshness should be verified.