Meta-Analysis on Tailored Antiplatelet Therapy After Endovascular Aneurysm Surgery

27 studies with 8,452 patients were analyzed to compare tailored versus standard antiplatelet regimens after endovascular intracranial aneurysm surgery. The meta-analysis, authored by figshare admin karger and last updated in May 2026, found tailored protocols significantly reduced thromboembolic events and major hemorrhage. The findings support a shift toward personalized antiplatelet strategies informed by platelet function testing and device technology.

Use Cases

• Compare the effectiveness of different antiplatelet strategies based on the study's meta-analysis results.
• Assess the safety profile of platelet function testing-guided therapy versus standard dual antiplatelet therapy.
• Evaluate outcomes for surface-modified flow diversion devices enabling single antiplatelet therapy.
• Inform clinical guideline development for personalized neurointerventional care based on the systematic review conclusions.

Strengths

• Analysis includes data from 27 studies and 8,452 patients.
• Meta-analysis employed subgroup and trial sequential analyses to assess robustness.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• The dataset is a 474.4 KB DOCX file containing supplementary material, not structured data.
• Column-level documentation is absent; field semantics must be inferred from the document.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of studies from PubMed, Embase, and Cochrane Library.

Freshness

Last updated 2026-05-14 05:55:40; freshness should be verified.