Plasma Equol Levels and Precancerous Colorectal Lesions in Japanese Residents

993 participants aged 40-79 from Izu Oshima, Japan, were analyzed for plasma equol levels and precancerous colorectal lesions via colonoscopy. The study, published in 2024, found no significant association between equol production status and lesion presence. This supplementary material includes the research methodology and results.

Use Cases

• Replicate statistical analysis of odds ratios for precancerous lesions based on the described cross-sectional study design.
• Investigate the relationship between equol production status and advanced colorectal lesions based on the inverse trend suggested in the results.
• Use the documented methodology for plasma equol analysis via gas chromatography-mass spectrometry as a reference for similar biomarker studies.
• Analyze the association between gut microbiota-dependent metabolites and colorectal carcinogenesis based on the study's framework and conclusions.

Strengths

• Includes data from 993 participants, providing a substantial sample size for analysis.
• Specifies a clear study population: residents aged 40-79 years in Izu Oshima, Japan.
• Reports precise statistical results, including an odds ratio of 1.04 with a 95% confidence interval of 0.77-1.40.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic bias inherent to the single study location in Japan.

Provenance

Source

figshare admin karger

Collection Method

Cross-sectional study with blood sample collection and colonoscopy screening.

Time Range

Data collection likely occurred prior to 2024 analysis.

Freshness

Last updated 2026-04-20 03:55:27; freshness should be verified.

Geography

Izu Oshima, Japan