Supplementary Material for: Association of Persistent Organic Pollutants Polychlorinated B

figshare admin karger provides supplementary material for a study analyzing the association of polychlorinated biphenyls (PCBs) and dioxins with cardiovascular-kidney-metabolic (CKM) syndrome and mortality. The material, last updated in April 2026, is a 654.6 KB DOCX file. The underlying study used data from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2012.

Use Cases

• Reviewing statistical methods for mixture effect analysis based on the description of weighted quantile sum and quantile g-computation.
• Examining mediation analysis results for inflammatory cells based on the described role of white blood cells, lymphocytes, and neutrophils.
• Assessing mortality risk associations based on the described Cox proportional hazards regression results for different CKM stages.
• Understanding the individual pollutant effects on CKM syndrome based on the reported risk percentages for specific PCBs and dioxins.

Strengths

• Study is based on nationally representative data from NHANES 2005-2012.
• Analysis includes multiple statistical methods: multivariable logistic regression, weighted quantile sum, quantile g-computation, and Cox regression.
• Provides specific risk percentages for individual pollutants (e.g., PCB138 associated with ~4% increased risk).

Limitations

• The dataset is a 654.6 KB DOCX file, suggesting it is likely textual documentation rather than raw data tables.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for direct data analysis.

Provenance

Source

National Health and Nutrition Examination Survey (NHANES)

Collection Method

Data on PCB and dioxin-like compound exposure and CKM syndrome were obtained from NHANES.

Time Range

2005-2012

Freshness

Last updated 2026-04-15 09:55:16; freshness should be verified.

Geography

United States (nationally representative)