Clinical and Molecular Details of a Pediatric Uveal Melanocytic Tumor

A figshare admin karger published a case report on 2026-05-09 detailing an unusual intraocular tumor in a child. The 577.0 KB PDF includes clinical findings, imaging (ultrasound, MRI), pathology, immunohistochemistry, and comprehensive molecular testing results from a single patient with 10-year follow-up. The tumor, provisionally named 'endopapillary uveal melanocytic tumor of childhood,' exhibited unique features without known genetic abnormalities associated with uveal melanoma.

Use Cases

• Comparative pathology analysis based on the described histopathologic examination of a densely pigmented tumor growing around vascular 'papillae'
• Radiology feature study based on the MRI scan details including T1 precontrast hyperintensity and T2-weighted low signal intensity
• Molecular oncology research based on the comprehensive genetic testing results from MSK-IMPACT and Archer Fusion testing that revealed no abnormalities
• Clinical case review for rare disease diagnosis based on the 10-year follow-up data showing no evidence of recurrence

Strengths

• Includes 10-year clinical follow-up data for a single patient case
• Contains multi-modal data: clinical, imaging (MRI, ultrasound), pathology, immunohistochemistry, and molecular profiling
• Molecular testing covered 468 known cancer genetic alterations via MSK-IMPACT
• Detailed case presentation including specific tumor dimensions (1.9 × 1.7-cm)

Limitations

• Dataset consists of a single case study (n=1), limiting statistical power
• Row count and column-level documentation are absent; field semantics must be inferred after download
• Data may reflect bias inherent to being a single case report from an unspecified institution

Provenance

Source

figshare

Collection Method

Clinical case study documentation including imaging, pathology, and molecular testing

Time Range

Case includes data from patient presentation at 7 months old through at least 6 years of follow-up

Freshness

Last updated 2026-05-09 13:55:09