Olfactory and Sonography Biomarkers for Parkinson's Disease in 202 Patients

A cross-sectional study of 89 Parkinson's disease patients and 113 healthy controls. The dataset includes olfactory function scores from the 16-item Sniffin' Sticks test and substantia nigra echogenicity measurements from transcranial sonography. It was authored by figshare admin karger and last updated on May 22, 2026.

Use Cases

• Training binary classification models to differentiate Parkinson's disease from healthy controls based on olfactory and sonography markers.
• Analyzing the relationship between age and olfactory function decline in a control population.
• Evaluating the combined diagnostic performance (sensitivity, specificity, accuracy) of multiple biomarkers.
• Investigating sex differences in olfactory function between patient and control groups.

Strengths

• Includes data from 202 total participants (89 patients, 113 controls), providing a basis for comparative analysis.
• Reports specific diagnostic performance metrics: 83.1% sensitivity, 95.6% specificity, and 90.1% accuracy for the combined markers.
• Uses standardized clinical tests: the 16-item Sniffin' Sticks test and transcranial sonography.
• Stratifies participants by age (≤60 and >60 years) for subgroup analysis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (246.2 KB), indicating limited scope and sample size.

Provenance

Source

figshare

Collection Method

Cross-sectional study with clinical assessments.

Freshness

Last updated 2026-05-22 09:55:22; freshness should be verified.