Systematic Review of Treatments for Crack Cocaine Use Disorder

33 studies, including 15 randomized controlled trials, were synthesized to compare interventions for crack cocaine addiction specifically. Contingency management showed significant results for improving abstinence and treatment retention, while pharmacological trials had variable outcomes. The review's methodology focused on distinguishing crack from cocaine use, covering literature from 2014 to July 2024.

Use Cases

• Comparing the effectiveness of contingency management versus pharmacological treatments based on reported outcomes.
• Assessing the risk of bias in clinical trials for crack cocaine use disorder based on Cochrane tool evaluations.
• Identifying research gaps in treatments for crack cocaine by analyzing the included study characteristics.
• Informing clinical guideline development for crack use disorder based on synthesized evidence from RCTs.

Strengths

• Follows PRISMA guidelines for systematic review, ensuring a structured methodology.
• Includes a specific analysis of 15 randomized controlled trials (RCTs) among the 33 total studies.
• Explicitly distinguishes between crack and cocaine use disorders, addressing a noted gap in the literature.

Limitations

• The majority of included RCTs had a moderate or high risk of bias (14 out of 15).
• Column names and dataset structure are not provided, limiting detailed data exploration.
• The dataset appears to be a single supplementary document, not a structured data table.

Provenance

Source

figshare admin karger

Collection Method

Systematic literature review searching Web of Science and Psychinfo.

Time Range

2014 to July 2024

Freshness

Last updated 2026-03-23.

Geography

Worldwide (studies included from all regions)