Supplementary Material for: Conventional and Molecular Approaches to Pediatric Wheat Aller

An East Mediterranean cohort of 63 children (median age 30 months) evaluated for IgE-mediated wheat allergy. The dataset, published by figshare admin karger, includes retrospective clinical analysis, skin prick test results, specific IgE levels, and molecular allergology data for components like Tri a 19 and Alpha-Amylase Inhibitors. It was last updated on 2026-05-20.

Use Cases

• Evaluating diagnostic cutoffs for wheat-specific IgE based on the reported 6.73 kU/L threshold.
• Assessing the predictive utility of molecular components like Tri a 19 and Alpha-Amylase Inhibitors for wheat allergy.
• Studying clinical characteristics and anaphylaxis rates in a pediatric multi-allergic population.
• Comparing sensitization profiles to related cereals like rye and barley within an allergic cohort.

Strengths

• Includes data from 63 pediatric patients with detailed clinical classification (30 allergic, 33 sensitized).
• Reports specific, statistically derived diagnostic cutoffs for tests like skin prick test (5 mm) and wheat sIgE (6.73 kU/L).
• Analyzes multiple diagnostic modalities: skin prick tests, ImmunoCAP, and the ALEX2 multiplex platform.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (14.7 KB), indicating limited raw data scope.

Provenance

Source

figshare admin karger

Collection Method

Retrospective analysis of children evaluated for IgE-mediated wheat allergy, using oral food challenges, skin prick tests, and molecular allergology.

Freshness

Last updated 2026-05-20 05:55:08; freshness should be verified.

Geography

East Mediterranean region