PRIDE BIOME Study: Infant Gut Microbiota and Socio-Emotional Development Over 4.5 Years

Longitudinal data from the PRIDE BIOME study tracks gut microbiome development in 81 infants over their first year of life and links it to socio-emotional development measured over 4.5 years. The dataset includes 5 microbiome sampling timepoints and 8 developmental assessments per individual. It was authored by figshare admin karger and last updated in April 2026.

Use Cases

• Modeling temporal trajectories of infant gut microbial diversity based on repeated 16S rRNA sequencing measurements.
• Investigating associations between specific bacterial genera like Bifidobacterium and socio-emotional development scores.
• Training predictive models for socio-emotional development outcomes using longitudinal microbiome and questionnaire data.

Strengths

• Longitudinal design with 5 microbiome measurements and 8 developmental assessments per infant over 4.5 years.
• Includes data from 81 participants (42 males) with covariates like sex, birth weight, and gestational age.
• Statistical results, including p-values and effect sizes for key genera, are provided in the description.

Limitations

• Row count and column-level documentation are unknown; field semantics must be inferred after download.
• The dataset is small at 354.3 KB, indicating a limited scope or summary-level data rather than raw sequences.

Provenance

Source

PRIDE (PRegnancy and Infant DEvelopment) BIOME study, a focus cohort within the larger prospective PRIDE Study.

Collection Method

Gut microbiome measured via V4 16S rRNA sequencing; socio-emotional development assessed via Ages and Stages Questionnaire: Social-Emotional (ASQ-SE).

Time Range

Microbiome data covers the first year of life (2, 4, 6, 9, 12 months); developmental data spans from 6 months to 5 years.

Freshness

Last updated 2026-04-22 11:55:13