Supplementary Material for: Distinct Histopathological and Transcriptomic Signatures of Ce

A multicenter retrospective study of 221 chronic rhinosinusitis patients, stratified into four phenotypes, conducted by figshare admin karger. The dataset includes clinical, histopathological, and transcriptomic data, with RNA sequencing performed on representative nasal tissues. The material was last updated on 2026-05-18.

Use Cases

• Compare clinical and radiological metrics across CRS phenotypes based on demographics, symptom scores, and CT metrics.
• Identify histopathological patterns like eosinophil-rich stromal remodeling based on structured histopathological features.
• Analyze transcriptomic signatures and biological pathways based on RNA sequencing data from nasal tissues.
• Investigate the molecular similarity between CCAD and other subtypes based on differentially expressed gene analysis.

Strengths

• Includes data from 221 eligible CRS patients across multiple clinical centers.
• Provides RNA sequencing data from representative nasal tissues (n=5 per group).
• Analyzes structured histopathological features such as basement membrane thickening and fibrosis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 65.1 KB, indicating limited primary data scope.

Provenance

Source

figshare admin karger

Collection Method

Multicenter retrospective study analyzing patient records, histopathology, and RNA sequencing.

Freshness

Last updated 2026-05-18 13:55:14; freshness should be verified