Supplementary Material for: Divergent renal benefits of SGLT2 inhibitors and mineralocorti

Supplementary PDF and DOC files for a systematic review and Bayesian network meta-analysis of 18 randomized controlled trials in non-diabetic kidney disease. The material, authored via figshare admin karger and last updated in April 2026, details comparative effects of SGLT2 inhibitors and mineralocorticoid receptor antagonists on eGFR slope, proteinuria, and blood pressure.

Use Cases

• Reviewing the statistical methodology and results of a Bayesian network meta-analysis based on the described 18 trials.
• Extracting quantitative findings on estimated glomerular filtration rate (eGFR) slope preservation for secondary analysis.
• Comparing reported treatment effects on urine protein-to-creatinine ratio (UPCR) and systolic blood pressure reduction.
• Examining safety parameter analyses, such as hemoglobin decrease and creatinine rise, mentioned in the conclusions.

Strengths

• Provides supplementary material for a peer-reviewed meta-analysis of 18 randomized controlled trials.
• Includes specific quantitative results, such as a mean difference of 12.1 mL/min/1.73 m²/year for eGFR slope with SGLT2i.
• Released under a permissive CC-BY-4.0 license, allowing for reuse and redistribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for computational analysis.
• The 2.4 MB size suggests the files are likely documents, not a structured data table.

Provenance

Source

figshare

Collection Method

Systematic review and Bayesian network meta-analysis of published randomized controlled trials.

Time Range

Temporal coverage of the included trials is not specified.

Freshness

Last updated 2026-04-24 07:55:25; freshness should be verified.

Geography

Geographic coverage of the included trials is not specified.