Supplementary Material for ABO-Incompatible Kidney Transplantation Plasmapheresis Study

230 consecutive ABO-incompatible living donor kidney transplants performed from September 2014 to April 2024. This supplementary material compares the efficacy and long-term prognosis of double filtration plasmapheresis (DFPP) versus plasma exchange (PE) for antibody clearance. The study reports outcomes including acute rejection, patient mortality, hospital stay duration, and effects on isoagglutinin titers.

Use Cases

• Comparing clinical outcomes of two plasmapheresis modalities based on reported incidence rates of acute rejection and patient mortality.
• Analyzing the relationship between antibody rebound and acute rejection risk based on the reported odds ratio.
• Studying the depletion of blood proteins like albumin and fibrinogen during different antibody clearance procedures.
• Evaluating the reduction in IgG and IgM isoagglutinin titers following single sessions of DFPP and PE.

Strengths

• Includes data from 230 consecutive transplants over a nearly 10-year period (September 2014 to April 2024).
• Reports specific statistical outcomes, such as a 6.43 times greater risk of AR with antibody rebound and an 85.8% lower risk with DFPP.
• Provides detailed comparison metrics, including hospital stay lengths (22 vs 42 days) and protein depletion levels.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 794.1 KB file size suggests the dataset is a document, likely containing text and tables, rather than a large structured data file.

Provenance

Source

figshare admin karger

Collection Method

Clinical study of consecutive ABO-incompatible living donor kidney transplants.

Time Range

September 2014 to April 2024

Freshness

Last updated 2026-05-14 07:55:45; freshness should be verified.

Geography

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