Meta-Analysis Data on Endovascular vs. Medical Stroke Treatment for Distal Occlusions

8936 patient records from a systematic review comparing endovascular treatment to best medical therapy for acute ischemic strokes due to distal medium vessel occlusions. The meta-analysis, performed by researchers and shared via figshare, includes data from three RCTs and 30 observational studies up to April 2025. It reports efficacy and safety outcomes including functional independence and symptomatic intracranial hemorrhage rates.

Use Cases

• Compare functional outcomes (mRS 0-1, mRS 0-2) between EVT and BMT based on the reported meta-analysis results
• Assess the risk of symptomatic intracranial hemorrhage associated with EVT based on the statistically significant odds ratio
• Analyze treatment outcomes for mild stroke patients (NIHSS <6) based on the subgroup analysis mentioned in the description
• Investigate the impact of posterior circulation occlusions and treatment timing (>4 hours) on outcomes based on the conclusion

Strengths

• Includes data from 8936 patients across 33 studies, providing a substantial sample size for meta-analysis
• Compares two distinct treatment arms: 4049 patients in EVT and 4887 in BMT
• Reports specific statistical outcomes with confidence intervals and p-values, such as the OR of 1.54 for sICH with EVT

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• The primary data files are in PDF and DOCX formats, which are not machine-readable without extraction
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare admin karger

Collection Method

Systematic review and meta-analysis of studies from Embase, PubMed, and Cochrane.

Time Range

Studies included up to April 2025.

Freshness

Last updated 2026-05-22 05:55:19; freshness should be verified