Fetal Haemodynamic MRI Data After Tadalafil Exposure in a Sheep Model

51.8 KB of supplementary material for a study on fetal tadalafil exposure. The data likely contains results from MRI scans on 9 pregnant ewes at 119-123 days gestational age, measuring blood flow and oxygenation. The material, authored by figshare admin karger and last updated in April 2026, supports findings on altered pulmonary haemodynamics.

Use Cases

• Analyze changes in pulmonary blood flow and ductus arteriosus flow based on haemodynamic measurements mentioned in the description
• Correlate fetal tadalafil concentrations with observed vascular changes based on LC-MS/MS data mentioned
• Study the impact of drug exposure on cerebral oxygen delivery based on carotid artery blood flow data mentioned
• Compare haemodynamic profiles between tadalafil and sildenafil exposure based on the study's conclusions

Strengths

• Data is associated with a controlled animal study involving 9 pregnant ewes.
• Includes specific gestational age ranges (116-123 days) and measurement techniques (MRI, LC-MS/MS).
• Released under a permissive CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 51.8 KB file size suggests limited raw data, likely containing text and figures rather than extensive datasets.

Provenance

Source

figshare

Collection Method

Data likely generated from fetal catheterisation surgery and MRI scans on a sheep model, as described in the methods.

Time Range

Experimental measurements taken at 119-123 days gestational age.

Freshness

Last updated 2026-04-16 05:55:30; freshness should be verified.

Geography

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