Global and Brazilian Regional Neuromyelitis Optica Prevalence Estimates

44 studies from 28 countries provide global prevalence estimates for Neuromyelitis Optica Spectrum Disorder (NMOSD). This supplementary material includes results from a systematic review, meta-analysis, and a new regional study in Rio de Janeiro, Brazil. The work was authored by figshare admin karger and last updated in April 2026.

Use Cases

• Analyze continent-specific pooled prevalence estimates for NMOSD, comparing the Americas, Asia, Europe, and Oceania.
• Compare crude prevalence figures, such as the 3.07 per 100,000 from the Brazilian regional study, against global meta-analysis results.
• Examine the range of capture-recapture and Bayesian posterior mean estimates (e.g., 3.53 to 5.60 per 100,000) from the Volta Redonda–Barra Mansa study.

Strengths

• Integrates data from 44 eligible studies across 28 countries, providing a broad international perspective.
• Includes a detailed regional population-based analysis covering 782,004 inhabitants in southeastern Brazil.

Limitations

• The dataset is very small at 65.9 KB, containing supplementary documentation rather than raw case-level data.
• Substantial heterogeneity is noted across included studies due to differences in diagnostic criteria and case-ascertainment strategies.
• Sample data and specific data columns are unavailable, limiting direct computational analysis.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of published studies, combined with a multi-source prevalence study in a Brazilian region.

Time Range

Studies reporting prevalence between 2000 and 2025.

Freshness

Last updated on 2026-04-03.

Geography

Global coverage from 28 countries, with specific regional data from the Volta Redonda–Barra Mansa area of Rio de Janeiro State, Brazil.