Global Trends in Early-Onset Dementia Burden: 1990-2030 Projections

Global data from the Global Burden of Diseases 2021 Study tracks the burden of early-onset dementia (EOD) in individuals aged 40–64 years from 1990 to 2021, with projections to 2030. It includes global and regional estimates for incidence, prevalence, disability-adjusted life years (DALYs), and deaths, analyzed by sex and sociodemographic index (SDI). The dataset reveals a more than doubling of global EOD cases over three decades and notable disparities across regions and demographic groups.

Use Cases

• Analyzing temporal trends in EOD incidence and prevalence based on age-standardized rates from 1990-2021.
• Comparing regional and sex-based disparities in EOD burden using sociodemographic index (SDI) and geographic breakdowns.
• Projecting future incidence rates to 2030 using the Bayesian age-period-cohort model.
• Assessing the impact of EOD through public health metrics like disability-adjusted life years (DALYs) and deaths.

Strengths

• Derived from the authoritative Global Burden of Diseases (GBD) 2021 Study, a large-scale modeling effort.
• Provides a long time series from 1990 to 2021 with future projections to 2030.
• Includes multiple standardized metrics: incidence, prevalence, DALYs, and deaths, enabling comprehensive burden assessment.

Limitations

• Column names and specific data structure are not provided in any source, limiting understanding of the dataset's granularity.
• The exact row count is unclear; one source lists a size of 151919 but no row count, while others list none.
• Relies on modeled estimates from the GBD study, which may incorporate assumptions and uncertainties.

Provenance

Source

Global Burden of Diseases (GBD) 2021 Study.

Collection Method

Systematic analysis using the Bayesian age-period-cohort (BAPC) model for estimation and projection.

Time Range

1990 to 2021, with projections to 2030.

Freshness

Last updated on 2026-03-25.

Geography

Global, with breakdowns by region, country, and SDI level.