Case Report: Growing Teratoma Syndrome in a Pediatric Pineal Tumor

A single medical case report detailing the diagnosis and treatment of a 12-year-old boy with a pineal mixed germ cell tumor. The report includes clinical history, MRI findings, histopathology results, and treatment outcomes. The document is a 790.2 KB PDF published under a CC-BY-4.0 license.

Use Cases

• Analyze clinical progression of growing teratoma syndrome based on the detailed case narrative.
• Study biomarker trends (Ki-67, AFP) in response to chemotherapy based on reported lab values.
• Review multimodal treatment protocols (ACNS1123, ACNS0122) for non-germinomatous germ cell tumors.
• Examine diagnostic challenges of pineal region tumors based on the described radiologic and histologic features.

Strengths

• Includes specific clinical metrics: Ki-67 index of 25% at diagnosis decreasing to 5% post-resection.
• Reports detailed treatment timeline and protocols (ACNS1123 chemotherapy, ACNS0122 radiotherapy).
• Provides concrete biomarker levels: serum AFP of 23.2 ng/mL.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect the inherent bias of a single, highly specific case report.

Provenance

Source

figshare admin karger

Collection Method

Clinical case documentation and analysis.

Time Range

Case presented in August 2024.

Freshness

Last updated 2026-05-20 07:55:08; freshness should be verified.