Supplementary Material for Homer 2 and NFATc1 in Muscle Regeneration

260 KB of supplementary material from a 2026 study on skeletal muscle regeneration in mice. The research from figshare investigates the role of Homer 2 protein in the calcineurin-NFAT pathway during muscle repair. Data includes immunofluorescence staining results for Homer 2, NFATc1, Pax7, and myogenin from mouse tibialis anterior muscles at 2, 4, and 6 days post-injury.

Use Cases

• Analyzing protein expression frequency changes over time based on the 2, 4, and 6-day post-injection time points
• Studying co-localization patterns between Homer 2 and satellite cell markers like Pax7 and myogenin
• Investigating the interaction between Homer 2 and NFATc1 via co-immunoprecipitation data
• Modeling the calcineurin-NFAT signaling pathway's role in muscle differentiation

Strengths

• Data is from a controlled experiment using 12-week-old male ICR mice with a sample size of n=6 per group.
• Includes temporal analysis across three specific time points (2, 4, and 6 days post-injection).
• Quantitative analysis performed by calculating immunoreactivity frequency per 500 nuclei.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is very small at 260.0 KB, indicating limited scope.
• Data may reflect bias inherent to the specific mouse model and experimental injury method.

Provenance

Source

figshare

Collection Method

Experimental data from immunofluorescence staining and co-immunoprecipitation of mouse tibialis anterior muscles.

Time Range

Data collected at 2, 4, and 6 days post-injection.

Freshness

Last updated 2026-06-04 07:55:07.