Supplementary Material for: IFTA as a predictor of renal outcome in patients with malignan

A multicenter cohort of 465 patients with malignant hypertension-related thrombotic microangiopathy (TMA) confirmed by renal biopsy. The data was collected from seven Chinese hospitals between 2008 and 2024, with a median follow-up of 24 months. It was used to evaluate interstitial fibrosis and tubular atrophy (IFTA) as a predictor for renal replacement therapy dependence and renal function recovery.

Use Cases

• Predicting renal replacement therapy dependence based on IFTA severity scores.
• Modeling time-to-event outcomes for renal function recovery using Kaplan-Meier analysis.
• Assessing hazard ratios for adverse renal outcomes via Cox proportional hazards models.
• Investigating the relationship between pathological findings (IFTA, global glomerulosclerosis) and clinical endpoints.

Strengths

• Contains data from 465 patients across seven hospitals, suggesting a multi-center design.
• Follow-up period has a reported median of 24 months.
• Statistical results, including hazard ratios and confidence intervals, are provided in the description.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The primary data file is a DOCX document (897.1 KB), which may not be in an analysis-ready tabular format.
• Data may reflect geographic and healthcare system bias inherent to the seven Chinese source hospitals.

Provenance

Source

figshare admin karger

Collection Method

Multicenter cohort study using data from patients with renal biopsy-confirmed mHTN-related TMA.

Time Range

2008 to 2024

Freshness

Last updated 2026-05-04 05:55:12; freshness should be verified.

Geography

Seven hospitals in China