Serum Cytokine Levels for IBD Patients with and without Venous Thromboembolism

226 patients from the Swiss IBD cohort study were examined, including 78 with documented venous thromboembolism (VTE) and 148 age- and sex-matched controls. The dataset contains quantified serum levels for 12 proinflammatory cytokines and detailed disease characteristics. The study, published on figshare under CC-BY-4.0, found a significant association between elevated IL-22 levels and VTE in IBD patients.

Use Cases

• Hypothesis generation for cytokine associations with thrombosis based on the 12 measured cytokines.
• Statistical analysis of biomarker differences between patient groups based on matched controls.
• Modeling disease activity and thromboembolic risk based on detailed disease characteristics mentioned in the description.

Strengths

• Includes 226 well-characterized patients from a clinical cohort study.
• Provides a 2:1 age- and sex-matched control group for the 78 VTE cases.
• Quantifies 12 specific proinflammatory cytokines, including IL-22 which showed a significant difference.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (262.2 KB), indicating limited scope.

Provenance

Source

Swiss IBD cohort study (SIBDCS), published via figshare by author 'figshare admin karger'.

Collection Method

Serum samples were analyzed using an array to quantify cytokine levels; disease characteristics were statistically analyzed.

Time Range

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Freshness

Last updated 2026-04-15 09:55:14; freshness should be verified.

Geography

Switzerland (implied by the Swiss IBD cohort study).