Supplementary Material for: Immunological Characteristics of Chinese Adult Patients with A

figshare admin karger published supplementary material for a 2026 study on anti-complement factor H autoantibodies (FHAAs) in adult patients with complement-mediated thrombotic microangiopathy (CM-TMA). The material likely contains data from 114 enrolled patients, including results on FHAA prevalence, epitope mapping, and clinical outcomes. The dataset is a 1017.3 KB PDF file.

Use Cases

• Analyze the prevalence of specific autoantibody epitopes based on the described SCR fragment reactivity data.
• Study the correlation between autoantibody levels and disease phase (active vs. remission) based on the reported AU/mL measurements.
• Investigate clinical outcomes and prognostic factors in FHAA-associated CM-TMA based on the described patient outcomes.
• Validate or compare epitope mapping methodologies for anti-complement factor H autoantibodies.

Strengths

• Includes data from a defined cohort of 114 adult CM-TMA patients.
• Reports specific prevalence percentages for 7 different CFH fragment epitopes.
• Provides quantitative autoantibody level data (AU/mL) comparing active and remission phases.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is a 1017.3 KB PDF, which may require manual extraction of structured data.

Provenance

Source

figshare admin karger

Collection Method

Data collected from 114 enrolled adult patients with CM-TMA; autoantibodies and epitopes detected via enzyme linked immunosorbent assay.

Time Range

null

Freshness

Last updated 2026-04-20 05:55:18; freshness should be verified.

Geography

The study focuses on Chinese adult patients.