Supplementary Material for: Long-term complete radiological response in a patient with bra

A 15 KB DOCX file contains a detailed case report and literature review on HER2-positive breast cancer. The report describes a patient with over 20 active brain metastases achieving a complete radiological response lasting more than 20 months after treatment with trastuzumab deruxtecan. The material was uploaded by figshare admin karger in April 2026 and is licensed under CC-BY-4.0.

Use Cases

• Reviewing clinical evidence for durable intracranial responses based on the described case of a heavily pretreated patient.
• Analyzing the potential role of antibody-drug conjugates crossing the blood-brain barrier based on the literature review.
• Studying treatment outcomes for patients with multiple (>20) brain metastases previously treated with WBRT and T-DM1.
• Evaluating the duration of complete radiological response (>20 months) in a specific clinical scenario.

Strengths

• The case report provides detailed clinical history including specific treatments (WBRT, T-DM1, T-DXd) and a quantified outcome (>20 months response).
• The material includes a literature review discussing the blood-brain barrier and systemic treatment limitations.
• The dataset is openly licensed (CC-BY-4.0) for reuse.

Limitations

• The dataset is a single case report (15 KB DOCX), representing a very limited scope of data.
• Row count and column-level documentation are absent; the content is unstructured narrative text.
• The data may reflect bias inherent to a single, exceptional clinical case.

Provenance

Source

figshare admin karger

Collection Method

Likely a clinical case report authored by medical professionals.

Freshness

Last updated 2026-04-29 05:55:42; freshness should be verified.