Case Report: GPP Flare Management with Intravenous and Subcutaneous Spesolimab

A single clinical case report details the treatment of a 72-year-old female patient with generalized pustular psoriasis (GPP). The report describes the use of intravenous spesolimab for an acute flare and subsequent long-term subcutaneous spesolimab therapy, authored by figshare admin karger and last updated on 2026-04-30. The dataset is a 747.9 KB PDF file.

Use Cases

• Analyze the clinical efficacy of IL-36R antibody therapy based on the described rapid symptom improvement within one week.
• Study long-term disease management strategies for chronic GPP based on the described subcutaneous dosing regimen every four weeks.
• Investigate post-flare complications and rehabilitation needs based on the described deterioration of functional status.

Strengths

• The report provides specific clinical details, including patient age (72), drug dosages (900 mg i.v., 300 mg s.c.), and treatment intervals (1 week apart, every 4 weeks).
• The dataset is openly licensed under CC-BY-4.0, permitting reuse and redistribution.
• The description includes a clear temporal sequence of treatment and patient outcomes.

Limitations

• The dataset is a single case report (n=1), which limits generalizability and statistical power.
• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Clinical case report documentation.

Freshness

Last updated 2026-04-30 05:55:09; freshness should be verified.