Wearable Pulse Rate and Activity Data from a Narcolepsy Type 1 Clinical Trial

110 participants with Narcolepsy Type 1 provided two weeks of baseline Empatica smartwatch data from the TAK-861 2001 phase 2 trial. The dataset contains minute-level pulse rate and motor activity data, processed into daily 24-hour, daytime, and nighttime averages. It supports methodological research on artifact screening and modeling the relationship between pulse rate and physical activity in a neurological disorder.

Use Cases

• Developing artifact screening and imputation methods for minute-level wearable pulse rate data.
• Modeling the association between daily motor activity and pulse rate using linear mixed-effects models.
• Evaluating the stability of derived daily metrics based on the proportion of valid minute-level data.
• Benchmarking preprocessing pipelines for clinical wearable data against a dataset with documented invalid observation rates.

Strengths

• Includes data from 110 participants with documented demographics (mean age 34.0, 51.8% female).
• Provides detailed data quality metrics, with 23.5% of minute-level observations flagged as invalid.
• Derived daily measures (e.g., mean pulse rates of 72.8, 83.3, 66.2 BPM) are explicitly calculated.
• Released under a permissive CC-BY-4.0 license, facilitating reuse.

Limitations

• Column names and raw data structure are not provided in the available metadata.
• The dataset appears to be supplementary material (DOCX format), which may limit direct computational analysis.
• The temporal coverage is limited to a two-week baseline period from a single clinical trial.

Provenance

Source

Data collected from the TAK-861-2001 randomized, phase 2 clinical trial (NCT05687903).

Collection Method

Empatica wrist-worn smartwatch data collected for two weeks at baseline, with epoch-level data screened for artifacts.

Time Range

Two-week baseline period (specific dates not provided).

Freshness

Last updated on 2026-03-24.

Geography

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