Sakuranetin Skin Cancer Study Data: Hematology, Antioxidant, and Inflammatory Markers

24 mice were divided into four groups for an eight-week study investigating sakuranetin's effects against DMBA-induced skin tumorigenesis. The dataset likely contains results from hematological evaluations, antioxidant enzyme levels, lipid peroxidation, and pro-inflammatory markers, as described in the supplementary material. The data was uploaded by figshare admin karger and last updated on 2026-04 09.

Use Cases

• Validate network pharmacology predictions based on the 53 identified sakuranetin targets.
• Analyze dose-response relationships for sakuranetin based on the 10 mg/kg and 20 mg/kg treatment groups.
• Correlate molecular docking binding affinities (e.g., COX-2: -9.2) with in vivo biomarker changes.
• Model anti-inflammatory effects based on pro-inflammatory marker levels (IL-1β, IL-6, TNF-α, COX-2).
• Study redox modulation based on antioxidant enzyme data (SOD, CAT, GSH) and lipid peroxidation.

Strengths

• Includes data from a controlled in vivo experiment with 24 mice across four defined groups.
• Measures multiple biological pathways: hematology, antioxidant enzymes, inflammation, and apoptosis.
• Integrates computational evidence (network pharmacology and molecular docking) with experimental results.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small at 519.1 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Experimental data from an in vivo mouse study, supplemented by computational analysis.

Time Range

Covers an eight-week experimental period.

Freshness

Last updated 2026-04-09 11:55:15; freshness should be verified.

Geography

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