Supplementary Material for Novel Glyceryl Ascorbate Derivative Effects on Keratinocytes

271.2 KB of supplementary material for a study investigating the effects of a novel glyceryl ascorbate derivative on human keratinocytes. The material, authored by figshare admin karger and last updated in April 2026, supports findings on cytokine inhibition and epidermal barrier function. It is available under a CC-BY-4.0 license.

Use Cases

• Validate experimental findings on interleukin-33 suppression based on the described gene expression analysis.
• Correlate protein-level changes with gene expression data based on the described Western blot and tissue staining.
• Analyze dose-dependent effects of 2GA16 on alarmin cytokines based on the described p-values and methodology.
• Study the relationship between filaggrin/involucrin expression and barrier function restoration based on the described results.

Strengths

• Includes statistically significant results (p < 0.01, p < 0.05) for key findings as described.
• Provides multi-method validation with gene expression, Western blot, and ex vivo tissue staining as described.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Supplementary material from an in vitro laboratory study on human keratinocytes.

Time Range

Study publication date is not specified; supplementary material updated April 2026.

Freshness

Last updated 2026-04-18 05:55:17; freshness should be verified.

Geography

Geographic coverage of the cell source is not specified.