Supplementary Material for a Rare Case of Vanishing Bile Duct Syndrome

1344499 bytes of supplementary material document a 77-year-old female patient's case of vanishing bile duct syndrome (VBDS) linked to long-term amoxicillin use. The dataset includes a detailed clinical narrative covering initial misdiagnosis as choledocholithiasis, endoscopic retrograde cholangiopancreatography (ERCP) treatment, biopsy-confirmed ductopenia, and nearly three years of follow-up with ursodeoxycholic acid. The patient ultimately passed away from unrelated comorbidities.

Use Cases

• Reviewing a detailed clinical timeline for a rare adverse drug reaction case study.
• Analyzing the diagnostic pathway from choledocholithiasis to biopsy-confirmed ductopenia.
• Studying long-term monitoring data on transaminase levels post-medication withdrawal.
• Teaching about drug-induced vanishing bile duct syndrome using a documented patient history.

Strengths

• Provides a complete, longitudinal case history covering diagnosis, treatment, and nearly three years of follow-up.
• Includes specific clinical details such as patient age, suspected drug (amoxicillin), and confirmatory biopsy findings.
• Dataset is openly licensed under CC-BY-4.0, facilitating reuse and sharing.

Limitations

• No column or structured data is provided; the dataset consists solely of a PDF document.
• Metadata is incomplete, lacking row count, organization, and a complete set of column names.
• The 'last updated' date of 2026-03-19 is in the future, indicating a potential metadata error.

Provenance

Source

figshare admin karger

Collection Method

Likely a published medical case report submitted as supplementary material.

Time Range

Covers a clinical case with follow-up over nearly three years.

Freshness

Last updated date is listed as 2026-03-19, which is inconsistent.

Geography

null