Supplementary Material on Plasmin-PAI-1 Role in Diabetic Vascular Calcification

7.3 MB of supplementary PDF data from a 2026 medical study investigating hyperglycemia-induced vascular calcification. The material supports findings on the roles of plasmin and plasminogen activator inhibitor-1 (PAI-1) in an in vitro model using vascular smooth muscle cells. It provides methodological details and results for the published research.

Use Cases

• Review the high-glucose culture methodology and PAI-1 expression results to validate experimental protocols.
• Analyze the exogenous plasmin stimulation data to understand its effects on AMPK and eNOS activation.
• Extract quantitative results on vascular calcification attenuation from the PAI-1 inhibition experiments.

Strengths

• Data is directly linked to a peer-reviewed medical study published in 2026.
• The 7.3 MB PDF provides detailed methodological context for the published findings.
• Released under a permissive CC BY 4.0 license for reuse and sharing.

Limitations

• The data is provided as a static PDF, not in a structured, machine-readable format like CSV.
• Sample size and specific quantitative results are embedded within the document, requiring manual extraction for analysis.
• Scope is limited to the specific in vitro model and experiments described in the associated paper.

Provenance

Source

figshare

Collection Method

Supplementary material generated for a published medical research study.

Time Range

null

Freshness

Last updated March 2026.

Geography

null