Case Report: ALK-Positive Squamous Cell Carcinoma Treated with Alectinib

A 2026 case report details the treatment of a 61-year-old non-smoking woman with primary unknown squamous cell carcinoma. The report, authored by figshare admin karger and published under CC-BY-4.0, describes a case where next-generation sequencing revealed ALK fusion gene positivity, leading to effective treatment with alectinib after initial chemotherapy. The dataset is a 54.1 KB DOCX file.

Use Cases

• Reviewing a clinical case of ALK fusion gene-positive squamous cell carcinoma based on the detailed patient history.
• Analyzing treatment efficacy of alectinib in a rare cancer subtype based on the described clinical outcome.
• Studying diagnostic pathways for cancers of unknown primary based on the described use of CT, PET-CT, and biopsy.
• Researching the application of next-generation sequencing for guiding targeted therapy based on the case narrative.

Strengths

• Case report provides a detailed clinical narrative, including patient history, diagnostic imaging, and treatment timeline.
• Dataset is openly licensed under CC-BY-4.0 for reuse.

Limitations

• Dataset is a single case report (54.1 KB), representing a very limited scope and sample size.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect the specific clinical bias inherent to a single case report from figshare.

Provenance

Source

figshare admin karger

Collection Method

Likely a documented clinical case study.

Freshness

Last updated 2026-05-13 05:56:23; freshness should be verified.