Severe PASH Syndrome Case Report with Multimodal Therapy Outcomes

A single clinical case report details the diagnosis and treatment of a 38-year-old woman with severe PASH syndrome. The report documents patient history, failed therapies, surgical procedures, and a successful eight-week multimodal treatment regimen. The report was authored by figshare admin karger and published on the figshare platform in April 2026.

Use Cases

• Analyze the documented triad of symptoms (pyoderma gangrenosum, acne conglobata, hidradenitis suppurativa) for pattern recognition in PASH syndrome diagnosis.
• Review the specific treatment sequence (IV ertapenem, corticosteroids, cyclosporine A) and its eight-week outcome timeline for clinical benchmarking.
• Study the reported patient metrics, such as pain level (VAS 8/10) and Hurley stage III classification, for severity assessment in similar cases.
• Examine the histopathology findings confirming neutrophilic inflammation to understand the disease's pathological basis.

Strengths

• Case report provides detailed, longitudinal clinical data for a single patient over a defined treatment period.
• Includes specific, quantifiable outcome measures like pain resolution and complete lesion healing within eight weeks.
• Documented under CC-BY-4.0 license, allowing for flexible reuse and sharing.

Limitations

• Dataset consists of a single case report (n=1), limiting statistical power and generalizability of findings.
• Data is contained within a 615.5 KB PDF, requiring text extraction for computational analysis.
• No structured data columns or sample data are provided, only narrative clinical text.

Provenance

Source

figshare, published by 'figshare admin karger'.

Collection Method

Clinical case report documenting patient examination, treatment, and outcomes.

Time Range

Covers the patient's presentation, treatment, and eight-week follow-up period.

Freshness

Last updated April 2026, indicating recent publication.