Supplementary Material: UK Biobank Obesity and Cardiovascular Risk Analysis

Supplementary data from a study redefining obesity using the 2024 EASO framework with morbidity stratification in the UK Biobank. The analysis includes data for 451,615 participants with a median follow-up of 15.1 years, evaluating all-cause mortality and major adverse cardiovascular events. The dataset was published on figshare by the author figshare admin karger in 2026 under a CC-BY-4.0 license.

Use Cases

• Validate the 2024 EASO obesity classification framework based on BMI, waist-to-height ratio, and morbidity status.
• Analyze hazard ratios for all-cause mortality across different adiposity categories.
• Investigate risk patterns for major adverse cardiovascular events (MACE) in relation to obesity phenotypes.
• Study the impact of morbidity on absolute risk across the full BMI spectrum.
• Replicate the study's Cox proportional hazards models for mortality and cardiovascular outcomes.

Strengths

• Analysis based on a large cohort of 451,615 UK Biobank participants.
• Longitudinal data with a median follow-up period of 15.1 years.
• Results include specific hazard ratios and confidence intervals for mortality and MACE.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic/temporal bias inherent to the UK Biobank cohort.

Provenance

Source

UK Biobank

Collection Method

Cohort study analysis using Cox proportional hazards models.

Time Range

Median follow-up of 15.1 years (specific start/end dates not provided).

Freshness

Last updated 2026-06-01 07:15:42; freshness should be verified.

Geography

United Kingdom (UK Biobank participants).