Cutaneous Vascular Responses to Local Heating in Post-Menopausal Females

Twenty-one post-menopausal females (10 receiving HRT, 11 not) underwent assessment of cutaneous vascular conductance at four body sites using laser-Doppler flowmetry. The dataset, shared under CC-BY-4.0, documents the nitric oxide contribution to vasodilation during local heating and pharmacological inhibition. It was last updated on 2026-05-22 by a figshare admin.

Use Cases

• Compare nitric oxide-dependent vasodilation between HRT and non-HRT groups based on the pharmacological inhibition protocol.
• Analyze regional heterogeneity in cutaneous vascular conductance across the chest, abdomen, forearm, and calf.
• Model the relationship between local skin temperature increases and microvascular response based on the described heating protocol.

Strengths

• Includes data from 21 human subjects with a defined split of 10 receiving HRT and 11 not.
• Measures cutaneous vascular conductance at four distinct anatomical sites (chest, abdomen, forearm, calf).
• Documents a specific experimental protocol involving local heating to 42°C and pharmacological NOS inhibition with L-NAME.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 37.2 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Data likely collected via controlled laboratory experiment using laser-Doppler flowmetry and intradermal microdialysis.

Freshness

Last updated 2026-05-22 09:55:14; freshness should be verified.