Review of Uveal Melanoma Metastasis Timing and Patient Outcomes

A literature review synthesizing clinicopathologic and molecular predictors of metastatic latency and survival outcomes in patients with uveal melanoma. The 46.3 KB document was authored by figshare admin karger and last updated on April 24, 2026. It is licensed under CC-BY-4.0.

Use Cases

• Identify clinical predictors of early metastasis based on features like age, sex, and tumor dimensions mentioned in the review.
• Analyze the association between genetic markers (e.g., monosomy 3, SF3B1 mutations) and metastatic latency for risk modeling.
• Investigate the impact of metastatic timing (early vs. late) on post-metastasis survival and treatment eligibility.
• Support the development of temporal risk stratification models by integrating molecular profiling with clinical staging.

Strengths

• Focuses on a specific clinical question regarding metastatic timing in uveal melanoma.
• Synthesizes findings on multiple predictors, including clinical, pathological, and molecular factors.
• Explicitly discusses implications for clinical management, such as surveillance intensity and adjuvant therapy selection.

Limitations

• The dataset is a 46.3 KB document, indicating a very limited scope and likely a summary review rather than primary data.
• Row count and column-level documentation are absent; the actual data structure and granularity are unknown.
• The data source is a literature review, which may reflect publication and selection biases inherent to the reviewed studies.

Provenance

Source

figshare admin karger

Collection Method

Literature review synthesizing existing studies.

Freshness

Last updated 2026-04-24 11:55:56