Impact of L-asparaginase Hypersensitivity in Pediatric Leukemia, 1997-2007

Supplementary Material for a study on L-asparaginase hypersensitivity in children with Acute Lymphoblastic Leukemia (ALL). The dataset includes records for 221 children treated between January 1997 and December 2007, with variables covering demographics, ALL characteristics, event-free survival, and desensitization procedures. It was published by figshare admin karger under a CC-BY-4.0 license.

Use Cases

• Analyze survival outcomes based on hypersensitivity status and desensitization procedures mentioned in the description.
• Study the frequency and timing of hypersensitivity reactions during different chemotherapy phases.
• Investigate associations between patient demographics and reported drug allergies.
• Compare long-term survival rates between patient groups with and without L-asparaginase allergy.

Strengths

• Includes data for 221 pediatric patients with a defined median age of 6.11 years.
• Reports specific survival statistics, such as a 10-year overall survival of 76.9% in the allergic group.
• Covers a 10-year treatment period from 1997 to 2007.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 31.2 KB, indicating limited scope.

Provenance

Source

figshare admin karger

Collection Method

Clinical records from children treated according to the Modified St Jude Total XIII protocol.

Time Range

January 1997 to December 2007

Freshness

Last updated 2026-05-22 09:55:29; freshness should be verified.