Five Case Reports of Thyroid Dysfunction Induced by Pembrolizumab

Five cancer patient case reports detail the development of thyroid dysfunction following pembrolizumab therapy. The retrospective analysis, published on figshare, includes longitudinal follow-up data on clinical trajectories and management outcomes. The supplementary material is a 784.4 KB PDF file last updated in May 2026.

Use Cases

• Analyzing clinical patterns of thyroid dysfunction based on heterogeneous onset timing described in the report
• Studying the association between baseline thyroid antibody status and hypothyroidism severity based on reported patient susceptibility
• Investigating the impact of early hormone replacement therapy on thyroid function stabilization based on the longitudinal follow-up findings

Strengths

• Includes longitudinal follow-up data for five patient cases.
• Focuses on a specific, clinically relevant adverse event of a widely used immunotherapy drug.
• The 784.4 KB PDF file provides detailed clinical narratives and analysis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's scale is limited to five case reports, offering insights but not generalizable population-level conclusions.

Provenance

Source

figshare admin karger

Collection Method

Retrospective analysis of patient cases.

Freshness

Last updated 2026-05-19 07:55:08; freshness should be verified.