Supplementary Table S1: CRISPR Screen and Sequencing Data for Immune Gene Therapy

Supplementary Table S1 from a study on rational design of immune gene therapy combinations. The dataset includes next-generation sequencing data from CRISPR screens, bulk RNA-seq, single-cell RNA-seq, and datasets related to adoptive cell therapy and immune checkpoint blockade. Authored by Feifei Zhang and shared under a CC-BY-4.0 license, this 25.5 MB Excel file was last updated on June 1, 2026.

Use Cases

• Identify tumor microenvironment modulators based on CRISPR activation screen data.
• Analyze gene expression changes in response to therapy using bulk and single-cell RNA-seq data.
• Correlate genetic perturbations with therapeutic outcomes from adoptive cell therapy and immune checkpoint blockade experiments.

Strengths

• Dataset is 25.5 MB in size, indicating a substantial amount of data.
• Includes multiple high-throughput data types: CRISPR screens, bulk RNA-seq, and single-cell RNA-seq.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely generated as part of an in vivo CRISPR activation screen study.

Freshness

Last updated 2026-06-01 07:24:40; freshness should be verified.