Supplementary Table S4: CRISPR Screen Data for MDM2-Amplified Liposarcoma

5.4 MB of CRISPR screen data from a study on MDM2-amplified liposarcoma, shared by Thijs Jalving on figshare. The dataset includes gene lists, read counts, and MAGeCK analysis outputs related to non-homologous end joining pathways and p53-mediated senescence. It was last updated on June 1, 2026.

Use Cases

• Identify essential and non-essential genes based on CRISPR screen read counts.
• Analyze gene knockout effects on drug sensitivity using MAGeCK output data.
• Investigate the role of the non-homologous end joining pathway in cancer cell survival.

Strengths

• Data is directly linked to a specific published study on liposarcoma and MDM2 amplification.
• Includes raw read counts and processed MAGeCK output, providing both primary and analyzed data.
• Shared under a permissive CC-BY-4.0 license for reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analyses.
• The 5.4 MB file size suggests a relatively small-scale screen.

Provenance

Source

figshare

Collection Method

Likely generated from CRISPR-Cas9 functional genomics screens.

Freshness

Last updated 2026-06-01 07:23:24; freshness should be verified.