Supplementary Table S4: TGF-β Pathway SNP Annotations for Colorectal Cancer Risk

12.1 KB Excel file containing pathway annotations for single nucleotide polymorphisms overrepresented in PANTHER pathways. The supplementary table was created by Joel Sanchez Mendez and last updated on June 2, 2026. It supports a novel pathway-based polygenic risk score method investigating red meat intake and colorectal cancer risk.

Use Cases

• Validating pathway-based polygenic risk score methods based on the described SNP annotations.
• Investigating the role of the TGF-β signaling pathway in colorectal cancer risk based on the described genetic associations.
• Replicating or extending the analysis of gene-environment interactions involving red meat intake.
• Annotating SNPs with biological pathways for functional genomics studies.

Strengths

• Data is openly available under a CC-BY-4.0 license.
• File size is 12.1 KB, indicating a focused and manageable dataset.
• Specific focus on the TGF-β pathway and colorectal cancer provides clear research context.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Joel Sanchez Mendez.

Collection Method

Likely derived from genetic association studies and pathway enrichment analysis.

Freshness

Last updated 2026-06-02 07:21:58; freshness should be verified.